Predictive Factors for Corneal Infiltrates With Continuous Wear of Silicone Hydrogel Contact Lenses

作者: Loretta Szczotka-Flynn , Sara M Debanne , Vinay K Cheruvu , Bill Long , Sally Dillehay

DOI: 10.1001/ARCHOPHT.125.4.488

关键词:

摘要: Objective To estimate the cumulative probability and risk factors for developing corneal infiltrates after up to 3 years of continuous wear (CW) with lotrafilcon A lenses. Methods Patients were fitted lenses followed years. The main outcome variable was first occurrence any infiltrative event in either eye. Cox proportional hazards regression used model as a function demographic biomicroscopy findings. Results total 317 patients participated this study. Kaplan-Meier unadjusted incidence infiltrate CW 5.7% (95% confidence interval [CI], 3.0%-8.4%) at end 1 year, 8.5% CI, 5.2%-11.9%) 2 years, 10.3% 6.6%-13.9%) Corneal staining limbal redness present affected eye on previous visit significantly associated development an (hazard ratios, 7.23 3.18; P  = .02, respectively). Conclusions may predict subsequent among contact lens patients. remaining free 89.7% 86.1%-93.4%).

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