P2X Receptors and Pain
作者： François Rassendren , Lauriane Ulmann
DOI: 10.1007/978-3-642-40282-1_30
关键词:
摘要: P2X receptors are ATP-gated channels and form the third major family of ligand-gated channels. Unlike other neurotransmitter-gated channels, have a widespread distribution outside brain involved in many physiological functions. A main function associated to is chronic pain. This chapter focuses on mechanisms underlying involvement pain, with particular emphasis contribution P2X4 P2X7 expressed by immune cells establishment network hyperexcitability
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North Ra, The P2X3 subunit: a molecular target in pain therapeutics. Current opinion in investigational drugs. ,vol. 4, pp. 833- 840 ,(2003)
F DIVIRGILIO, Liaisons dangereuses : P2X7 and the inflammasome Trends in Pharmacological Sciences. ,vol. 28, pp. 465- 472 ,(2007) , 10.1016/J.TIPS.2007.07.002
Geoffrey Burnstock, The purinergic nerve hypothesis. Ciba Foundation symposium. pp. 295- 314 ,(1977) , 10.1002/9780470720301.CH17
Debra A. Cockayne, Sara G. Hamilton, Quan-Ming Zhu, Philip M. Dunn, Yu Zhong, Sanja Novakovic, Annika B. Malmberg, Gary Cain, Amy Berson, Laura Kassotakis, Linda Hedley, Wilhelm G. Lachnit, Geoffrey Burnstock, Stephen B. McMahon, Anthony P. D. W. Ford, Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature. ,vol. 407, pp. 1011- 1015 ,(2000) , 10.1038/35039519
M. Murgia, S. Hanau, P. Pizzo, M. Rippa, F. Di Virgilio, Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor. Journal of Biological Chemistry. ,vol. 268, pp. 8199- 8203 ,(1993) , 10.1016/S0021-9258(18)53082-9
Jianguo G. Gu, Amy B. MacDermott, Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses. Nature. ,vol. 389, pp. 749- 753 ,(1997) , 10.1038/39639
G Collo, RA North, E Kawashima, E Merlo-Pich, S Neidhart, A Surprenant, G Buell, Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels The Journal of Neuroscience. ,vol. 16, pp. 2495- 2507 ,(1996) , 10.1523/JNEUROSCI.16-08-02495.1996
Kenichiro Nagata, Toshiyasu Imai, Tomohiro Yamashita, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief Molecular Pain. ,vol. 5, pp. 20- 20 ,(2009) , 10.1186/1744-8069-5-20
Geoffrey Burnstock, John N Wood, Purinergic receptors: their role in nociception and primary afferent neurotransmission. Current Opinion in Neurobiology. ,vol. 6, pp. 526- 532 ,(1996) , 10.1016/S0959-4388(96)80060-2
Arthur M. Butt, ATP: A ubiquitous gliotransmitter integrating neuron–glial networks Seminars in Cell & Developmental Biology. ,vol. 22, pp. 205- 213 ,(2011) , 10.1016/J.SEMCDB.2011.02.023