ADIPONECTIN VERSUS THIAZOLIDINEDIONES AND ANGIOTENSIN RECEPTOR BLOCKERS

摘要: Adipose tissue has gained great attention during the last decade. It represents not only a depot for energy stores, but also releases adipocytokines regulating disposal and can therefore be considered from therapeutic point of view. Hypoadiponectemia is an independent threat development metabolic syndrome. When subjects treated with antidiabetic (Thiazolidinediones) antihypertensive (angiotensin receptor blocker) agents , plasma concentration adiponectin, component adipocytokines, directly proportional to values these drugs. The prevalance hypertension T2DM mounting unprecedented degree in both developing advanced countries, therefore, there dire need find safer economical regimes treatment ailments, intensive research underway this purpose. PPARγ serves as common link actions ADN, TZDs ARBs when exerting their effects, it responsible stimulation adiponectin receptors, thus ultimately enhancing levels plasma. This review aims elucidate role, use ARBs, ADN convenient approach co-morbidities unanimous or single remedy comparative