Homocysteine and Mitochondria in Cardiovascular and Cerebrovascular Systems

作者: Peter Kaplan , Zuzana Tatarkova , Monika Kmetova Sivonova , Peter Racay , Jan Lehotsky

DOI: 10.3390/IJMS21207698

关键词:

摘要: Elevated concentration of homocysteine (Hcy) in the blood plasma, hyperhomocysteinemia (HHcy), has been implicated in various disorders, including cardiovascular and …

参考文章(133)
Natia Qipshidze, Alexander Ovechkin, Utpal Sen, Neetu Tyagi, Walter Rodriguez, Suresh C Tyagi, Cystathionine beta synthase gene dose dependent vascular remodeling in murine model of hyperhomocysteinemia International journal of physiology, pathophysiology and pharmacology. ,vol. 3, pp. 210- 222 ,(2011)
Gurumayum Suraj Sharma, Tarun Kumar, Tanveer Ali Dar, Laishram Rajendrakumar Singh, None, Protein N-homocysteinylation: From cellular toxicity to neurodegeneration. Biochimica et Biophysica Acta. ,vol. 1850, pp. 2239- 2245 ,(2015) , 10.1016/J.BBAGEN.2015.08.013
Pradip K. Kamat, Anuradha Kalani, Suresh C. Tyagi, Neetu Tyagi, Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells. Journal of Cellular Physiology. ,vol. 230, pp. 378- 394 ,(2015) , 10.1002/JCP.24722
Neetu Tyagi, Natia Qipshidze, Charu Munjal, Jonathan C. Vacek, Naira Metreveli, Srikanth Givvimani, Suresh C. Tyagi, Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia. Journal of Molecular Neuroscience. ,vol. 47, pp. 128- 138 ,(2012) , 10.1007/S12031-011-9695-Z
Joanna Perła-Kaján, Łukasz Marczak, László Kaján, Paweł Skowronek, Tomasz Twardowski, Hieronim Jakubowski, Modification by Homocysteine Thiolactone Affects Redox Status of Cytochrome c Biochemistry. ,vol. 46, pp. 6225- 6231 ,(2007) , 10.1021/BI602463M
Emilene B.S. Scherer, Aline Andrea Cunha, Janaína Kolling, Maira J. Cunha, Felipe Schmitz, Angela Sitta, Daniela D. Lima, Débora Delwing, Carmem R. Vargas, Angela T.S. Wyse, Development of an animal model for chronic mild hyperhomocysteinemia and its response to oxidative damage. International Journal of Developmental Neuroscience. ,vol. 29, pp. 693- 699 ,(2011) , 10.1016/J.IJDEVNEU.2011.06.004
Ottar Nygård, Stein Emil Vollset, Helga Refsum, Inger Stensvold, Aage Tverdal, Jan Erik Nordrehaug, Per Magne Ueland, Gunnar Kvåle, Total Plasma Homocysteine and Cardiovascular Risk Profile JAMA. ,vol. 274, pp. 1526- 1533 ,(1995) , 10.1001/JAMA.1995.03530190040032
Jessica A. Sipkens, Paul A. J. Krijnen, Christof Meischl, Saskia A. G. M. Cillessen, Yvo M. Smulders, Desirée E. C. Smith, Cindy P. E. Giroth, Marieke D. Spreeuwenberg, René J. P. Musters, Alice Muller, Cornelis Jakobs, Dirk Roos, Coen D. A. Stehouwer, Jan A. Rauwerda, Victor W. M. van Hinsbergh, Hans W. M. Niessen, Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis Apoptosis. ,vol. 12, pp. 1407- 1418 ,(2007) , 10.1007/S10495-007-0077-5