The CHOLEGAS study: multicentric randomized, blinded, controlled trial of gastrectomy plus prophylactic cholecystectomy versus gastrectomy only, in adults submitted to gastric cancer surgery with curative intent.

摘要: Background: The incidence of gallstones and gallbladder sludge is known to be higher in patients after gastrectomy than general population. This probably related surgical dissection the vagus nerve branches anatomical gastrointestinal reconstruction. Therefore, some surgeons perform routine concomitant cholecystectomy during standard surgery for gastric malignancies. However, not all who are diagnosed have cholelithiasis cancer will develop symptoms or require additional treatments a laparoscopic feasible even those underwent previous surgery. At present, no randomized study has been published decision management left each surgeon preference. Design: controlled investigation. performed General Oncologic Surgery, Department Oncology – Azienda Ospedaliero-Universitaria Careggi Florence Italy, large teaching institution, with participation accept involved in, together other Italian Surgical Centers, on behalf GIRCG (Italian Research Group Gastric Cancer). into two groups: first group patient submitted prophylactic curable (subtotal total gastrectomy), while second he/she only. Trial Registration: ClinicalTrials.gov ID. NCT00757640