Fusion Proteins for Half-Life Extension

作者: Stefan R. Schmidt

DOI: 10.1002/9781118354599.CH6

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参考文章(75)
Paul R. Hinton, Joanna M. Xiong, Mary G. Johlfs, Meina Tao Tang, Stephen Keller, Naoya Tsurushita, An engineered human IgG1 antibody with longer serum half-life. Journal of Immunology. ,vol. 176, pp. 346- 356 ,(2006) , 10.4049/JIMMUNOL.176.1.346
Jianfeng Xu, Shigeru Okada, Li Tan, Kenneth J. Goodrum, John J. Kopchick, Marcia J. Kieliszewski, Human growth hormone expressed in tobacco cells as an arabinogalactan-protein fusion glycoprotein has a prolonged serum life Transgenic Research. ,vol. 19, pp. 849- 867 ,(2010) , 10.1007/S11248-010-9367-8
Thomas Weimer, Wilfried Wormsbächer, Ulrich Kronthaler, Wiegand Lang, Uwe Liebing, Stefan Schulte, Prolonged in-vivo half-life of factor VIIa by fusion to albumin. Thrombosis and Haemostasis. ,vol. 99, pp. 659- 667 ,(2008) , 10.1160/TH07-08-0525
Pierpaolo Correale, Maria Grazia Cusi, Pierosandro Tagliaferri, Immunomodulatory properties of anticancer monoclonal antibodies: is the 'magic bullet' still a reliable paradigm? Immunotherapy. ,vol. 3, pp. 1- 4 ,(2011) , 10.2217/IMT.10.92
Jonas L. Fast, Amanda A. Cordes, John F. Carpenter, Theodore W. Randolph, Physical Instability of a Therapeutic Fc Fusion Protein: Domain Contributions to Conformational and Colloidal Stability Biochemistry. ,vol. 48, pp. 11724- 11736 ,(2009) , 10.1021/BI900853V
Jonathan Zalevsky, Aaron K Chamberlain, Holly M Horton, Sher Karki, Irene W L Leung, Thomas J Sproule, Greg A Lazar, Derry C Roopenian, John R Desjarlais, Enhanced antibody half-life improves in vivo activity Nature Biotechnology. ,vol. 28, pp. 157- 159 ,(2010) , 10.1038/NBT.1601
Mohammed F. Shamji, Helawe Betre, Virginia B. Kraus, Jun Chen, Ashutosh Chilkoti, Rajeswari Pichika, Koichi Masuda, Lori A. Setton, Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. Arthritis & Rheumatism. ,vol. 56, pp. 3650- 3661 ,(2007) , 10.1002/ART.22952
A Wunder, G Stehle, H Sinn, H Schrenk, D HoffBiederbeck, F Bader, E Friedrich, P Peschke, W MaierBorst, D Heene, Enhanced albumin uptake by rat tumors. International Journal of Oncology. ,vol. 11, pp. 497- 507 ,(1997) , 10.3892/IJO.11.3.497
F. A. Fares, N. Suganuma, K. Nishimori, P. S. LaPolt, A. J. Hsueh, I. Boime, Design of a long-acting follitropin agonist by fusing the C-terminal sequence of the chorionic gonadotropin beta subunit to the follitropin beta subunit. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 4304- 4308 ,(1992) , 10.1073/PNAS.89.10.4304