NITRIC OXIDE SYNTHASE 1 MRNA: TISSUE-SPECIFIC VARIANTS FROM RAT WITH ALTERNATIVE FIRST EXONS

摘要: We cloned a novel alternative first exon for nitric oxide synthase 1 (NOS1) that is specific kidney and two second exons which can be inserted between the kidney-specific currently numbered 2. The were localized within 17 kb upstream of 2, their flanking regions boundaries 2 sequenced. NOS1 mRNAs starting with four additional characterized respect to tissue distribution splicing. Altogether, at least 11 different splice variants found. Those present in mainly lacking