Myocardial Calcium and Magnesium in Acute Ischemic Injury

摘要: Abstract The effect of ischemic injury on calcium and magnesium distribution in dog myocardial cells was investigated tissue damaged by occlusion the circumflex branch left coronary artery for 60 minutes or 40 followed 20 reperfusion arterial blood. No significant change concentration these cations noted permanently ischemic, irreversibly injured cells, but markedly increased killed an episode transient ischemia. Tissue water sodium also were decreased significantly ischemia model. Investigation localization Ca-- cellular fractionation chemical analysis as well electron miscroscopy microincineration showed that much it localized dense bodies within mitochondria. Within intramitochondrial bodies, appeared to be a precipitate yet undefined form phosphate.