Endometriosis: Use of a new CA 125 assay in the diagnosis of endometriosis

作者: M.D. Hornstein , B.L. Harlow , P.P. Thomas , J.H. Check

DOI: 10.1093/OXFORDJOURNALS.HUMREP.A136064

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摘要: Serum CA 125 concentrations are elevated in some women with endometriosis; however, the low sensitivity and specificity of assay have made it impractical to use as a diagnostic test for endometriosis. Recently second-generation has been developed. The purpose this study was compare serum without endometriosis using both older new determine if concentration improves clinical utility diagnosis A total 123 patients endometriosis, pelvic pain or infertility were enrolled. Blood drawn cycle preceding laparoscopy laparotomy, found by newer assays correlated patients' stage revised American Fertility Society classification determined highly (r = 0.96). slightly improved assay; did not dramatically improve detection

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