Relatedness of wildlife and livestock avian isolates of the nosocomial pathogen Acinetobacter baumannii to lineages spread in hospitals worldwide

摘要: The natural habitats and potential reservoirs of the nosocomial pathogen Acinetobacter baumannii are poorly defined. Here, we put forth tested hypothesis avian A. baumannii. We screened tracheal rectal swab samples from livestock (chicken, geese) wild birds (white stork nestlings) isolated 3% sampled chicken (n = 220), 8% geese 40) 25% white nestlings 661). Virulence selected isolates was comparable to that clinical in Galleria mellonella infection model. Whole genome sequencing revealed close relationship an antibiotic-susceptible isolate Germany with a multidrug-resistant human China additional linkages between related international clonal lineages. Moreover, identified United States. Multilocus sequence typing disclosed further kinship isolates. Avian do not form distinct clade within phylogeny baumannii, instead they diverge into different Further, provide evidence is constantly present occupied by storks. Collectively, our study suggests could be zoonotic organism may disseminate livestock.