Preparation and characteristics of Tryptophan‐imprinted Fe3O4/P(TRIM) composite microspheres with magnetic susceptibility by inverse emulsion–suspension polymerization

摘要: Tryptophan-imprinted Fe3O4/P(TRIM) composite microspheres with magnetic susceptibility (MS-SMIPs) were prepared by inverse emulsion–suspension polymerization, according to the principle of molecular imprinting technique, using magnetite Fe3O4 particles as magnetically susceptible component, methacrylic acid (MAA) and acrylamide (AM) functional monomers, trimethylolpropane trimethacrylate (TRIM) polymeric matrix components, hydroxy ethyl cellulose (HEC) dispersant. The external morphology inner structure MS-SMIPs observed SEM. SEM photographs showed that resulting regularly spherical in had a large quantity microvoids inside. effects amount on particle size investigated detail. results indicated affected distribution obviously. characteristics measured vibrating sample magnetometer, certain response fields. Adsorption properties, recognition selectivity, regeneration selectivity tyrosine phenylalanine control molecules, characterized high performance liquid chromatography. It was shown exhibited good for tryptophan, relative separation factor (β) 2.75, also higher 1.83 1.80 first second regeneration, respectively. effect monomers investigated, mechanism analyzed. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 99: 3241–3250,