Sensitivity analysis in economic evaluation: a review of published studies.

摘要: A structured methodological review of journal articles published in 1992 was undertaken to determine whether recently economic evaluation studies deal systematically and comprehensively with uncertainty. Ninety three were identified from a range searches including computerised search the MEDLINE CD-Rom database. Articles reviewed how they had handled uncertainty in: a) data sources; b) generalisability; c) extrapolation; d) analytic method. subsequently assessed represented this terms overall results their analysis. Finally, rated on basis performance respect dealing uncertainty. Despite numerous books devoted appropriate methods be employed by analysts conducting evaluation, 22 (24%) failed consider at all 35 (38%) sensitivity analysis manner judged as inadequate. In all, 36 (39%) have given least an adequate account 13 (14%) those provided good uncertainty. Such disappointing may reflect general lack detail much literature concerning should applied presented. Journal editors readers acquaint themselves for handling order that can critically evaluate extent which authors allowed uncertainties inherent