Electrochemical detection of bovine immunoglobulins G to determine passive transfer of antibodies to calves.

摘要: Bovine antibodies, such as immunoglobulin G (IgG), cannot pass the placental barrier and are not transferred from mother to foetus, in utero. Instead a calf must absorb antibodies following ingestion of colostrum postpartum. Failure Passive Transfer (FPT) is condition that predisposes calves development disease increases risk mortality. Thus, continuous early monitoring IgG absorption calf, within first 6 12 hours life, imperative allow faster treatment prevent FPT. In this paper, we present label-free impedimetric immunosensor device for bovine serum demonstrate its suitability determine FPT new-born calves. The developed sensors were challenged discriminate between new born sera, both pre- post-colostrum feeding, demonstrated efficient detection under 15 minutes. Such could enable rapid determination FPT, thereby improving calves' vitality survival rate.