Inhibition of cell proliferation in renal failure and its significance to the uraemic syndrome: a review.

摘要: The effect of acute and chronic renal failure on cell proliferation in rapidly dividing tissues has been examined man animal models. evidence reviewed supports the hypothesis that results a general inhibition proliferation. Cell population kinetic studies gastrointestinal skin epithelia experimental show prolongation generation cycle. Less detailed investigations other proliferative systems indicate an inhibitory within generative compartment erythroid series, lymphoid tissue, seminiferous wound granulation tissue. This appears partly responsible for anaemia impaired healing may contribute to abnormal immune responses, tract lesions male sterility found failure.