Hereditary colorectal cancer syndromes: Epidemiological studies on Peutz-Jeghers syndrome & Lynch syndrome

作者: Margot van Lier

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摘要: textabstractColorectal cancer (CRC) is the second most common malignancy among women after breast cancer, and third men lung prostate cancer in European Union. In Netherlands, approximately 10000 cases are diagnosed each year. CRC moreover associated with high mortality ranks to as a cause of cancer-related in Europe.1 results from both genetic environmental factors. Genetic factors a major disease 20% CRC cases, spectrum ranging ill-defined familial aggregation without detectable disease-causing mutation (classified as CRC), well-defined autosomal dominant inherited syndromes.

参考文章(264)
Peter Beighton, Greta Beighton, de la Chapelle, A. The Person Behind the Syndrome. pp. 209- 209 ,(1997) , 10.1007/978-1-4471-0925-9_118
Uroš Potočnik, Damjan Glavač, Rastko Golouh, Metka Ravnik-Glavač, Causes of microsatellite instability in colorectal tumors Cancer Genetics and Cytogenetics. ,vol. 126, pp. 85- 96 ,(2001) , 10.1016/S0165-4608(00)00399-X
K R Cho, T D Kessis, L Hedrick, R T Burks, Microsatellite instability in endometrial carcinoma. Oncogene. ,vol. 9, pp. 1163- 1166 ,(1994)
Anil K. Rustgi, Gastrointestinal cancers : biology, diagnosis, and therapy Lippincott-Raven. ,(1995)
Robert T. Croyle, J. A. Skelton, Mental Representation in Health and Illness ,(2011)
Howard Leventhal, Michael Diefenbach, The Active Side of Illness Cognition Springer, New York, NY. pp. 247- 272 ,(1991) , 10.1007/978-1-4613-9074-9_11
Ada Chen, Hiun Suk Chae, Guoren Deng, Joe Hong, Young S. Kim, Methylation of CpG in a Small Region of the hMLH1 Promoter Invariably Correlates with the Absence of Gene Expression Cancer Research. ,vol. 59, pp. 2029- 2033 ,(1999)
Daniel R. McGrath, Allan D. Spigelman, Preventive measures in Peutz-Jeghers syndrome Familial Cancer. ,vol. 1, pp. 121- 125 ,(2001) , 10.1023/A:1013896813918
Schielen Pcji, Koster Mph, Elvers Lh, Loeber Jg, Downsyndroom-kansbepaling met de eerstetrimester-combinatietest 2004-2006 (deels 2007) Rijksinstituut voor Volksgezondheid en Milieu RIVM. ,(2009)
David S. Alberts, Nissi M. Varki, Goli Samimi, William J. Hoskins, Daniel Fink, Stephen B. Howell, Amreen Husain, Analysis of MLH1 and MSH2 expression in ovarian cancer before and after platinum drug-based chemotherapy. Clinical Cancer Research. ,vol. 6, pp. 1415- 1421 ,(2000)