作者: Margot van Lier
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摘要: textabstractColorectal cancer (CRC) is the second most common malignancy among women after breast cancer, and third men lung prostate cancer in European Union. In Netherlands, approximately 10000 cases are diagnosed each year. CRC moreover associated with high mortality ranks to as a cause of cancer-related in Europe.1 results from both genetic environmental factors. Genetic factors a major disease 20% CRC cases, spectrum ranging ill-defined familial aggregation without detectable disease-causing mutation (classified as CRC), well-defined autosomal dominant inherited syndromes.