Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster.

作者: Linda Partridge , Nik Prowse , Patricia Pignatelli

DOI: 10.1098/RSPB.1999.0630

关键词:

摘要: Ageing is the decline in survival probability and fertility later adult life. It can evolve through mutation accumulation pleiotropy. Artificial selection by age at reproduction a useful method for detecting effects of pleiotropy, producing lines that differ their rate ageing further analysis. However, approach has encountered difficulties from gene-environment interaction inadvertent selection. We have produced new set Drosophila melanogaster, breeding either 'young' or 'old' adults, avoiding some present previous studies. Breeding older adults resulted an evolutionary increase but, contrary to all studies using this method, no late-life fertility. The was accompanied early life, confirming importance pleiotropy evolution ageing. Contrary studies, there were correlated responses pre-adult period; development time, larval competitive ability size achieved did not between two regimes.

参考文章(31)
Aziz A. Khazaeli, James W. Curtsinger, Marc Tatar, Daniel E. L. Promislow, Age-Specific Patterns of Genetic Variance in Drosophila Melanogaster. II. Fecundity and Its Genetic Covariance with Age-Specific Mortality Genetics. ,vol. 143, pp. 849- 858 ,(1996) , 10.1093/GENETICS/143.2.849
Daniel E.L. Promislow, Marc Tatar, Mutation and senescence: where genetics and demography meet Genetica. ,vol. 102, pp. 299- 314 ,(1998) , 10.1023/A:1017047212008
Evolution of senescence: late survival sacrificed for reproduction. Philosophical Transactions of the Royal Society B. ,vol. 332, pp. 15- 24 ,(1991) , 10.1098/RSTB.1991.0028
L. D. Mueller, Evolution of accelerated senescence in laboratory populations of drosophila Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 1974- 1977 ,(1987) , 10.1073/PNAS.84.7.1974
B. Charlesworth, K. A. Hughes, Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 6140- 6145 ,(1996) , 10.1073/PNAS.93.12.6140
Leo S Luckinbill, Michael J Clare, Selection for life span in Drosophila melanogaster Heredity. ,vol. 55, pp. 9- 18 ,(1985) , 10.1038/HDY.1985.66