Antitonic agent for ciliary muscle

摘要: (57) [Problem] To provide a novel drug having selective action of relaxing ciliary muscle tone. SOLUTION: An active ingredient is represented by the following general formula (I): (The symbols in have meanings: Ring A: aryl group; cycloalkyl cycloalkenyl group, etc .; X: single bond or methylene R 1 : halogen atom; hydroxyl lower alkoxy carboxyl Lower alkoxycarbonyl acyl mercapto group and like; 2 hydrogen; alkyl 1: 0 1; integer 3; n: 2. A) tone agent comprising quinuclidine derivative (1), salt thereof quaternary ammonium thereof;