Tumor Lysis Syndrome in Limited-Stage Small-Cell Lung Cancer

摘要: We report a case of 70-year-old woman, with 56 pack-year smoking history, who presented an 8-week history progressively worsening shortness breath, cough, pleuritic chest pain, and 18-pound weight loss. A radiograph showed large opacification suggestive right-sided mediastinal mass. Positron emission tomography computed demonstrated heterogeneous, intensely F-18-fluorodeoxyglucose-avid posterior mass, measuring 74 × 60 mm in transaxial dimensions, 114 18 coronal dimensions. The mass e xtended from the level aortic arch to left atrium inferiorly caused significant compression displacement proximal midesophagus atrium, no evidence disease outside thorax. Bronchoscopic biopsy confirmed small-cell lung cancer (SCLC). Her radiographic studies revealed limited SCLC, concurrent chemoradiotherapy was recommended. patient initiated on chemotherapy cisplatin plus etoposide; radiotherapy scheduled start