Integration of Multimodality Approaches in the Management of Malignant Pleural Mesothelioma

摘要: More than half a century after the first descriptions of mesothelioma as pathologic entity, satisfactory treatment is still elusive. Although relatively uncommon, incidence will most likely increase over next 10-20 years. Advances have been made in understanding pathogenesis, diagnosis, and staging, but they not translated into markedly improved survival. Some use palliative primary means therapy even now. On other hand, cadre individuals studied how surgery, chemotherapy, radiation affect disease. each individual modality has had limited success by itself, multimodality approach documented to improve survival quality life. In addition, intriguing discoveries immunology gene profiling promise hope for further improvement. this article, we illustrate current views on integrating these different approaches delineate areas active research.