Pituitary and serum growth hormone during undernutrition and catch-up growth in young rats.

摘要: Sprague-Dawley rats at birth were redistributed among nursing mothers, 4 to some, 16 others. After 21 days, they studied by sex and nutritional state using a heterologous radioimmunoassay for growth hormone (GH) content of pituitary gland plasma. Greater access milk resulted in mean body weights males females 63 ± 1 g contrasting with 34 2, p < 0.01,and 3.0 0.07 mg, 2.0 0.06, 0.01. Better nutrition was attended plasma GH 14 ng/ml, contrast 2 ng/ml the undernourished. There highly significant differences total (257 12 μg/gland well-fed; 88 6 undernourished). During two weeks free food, from per mother group grew 5 times their previous rate (7.5 day vs 1.5 g) nearly overtook previously better-fed group; dietary repletion highest observed, ho...