Cell membrane amino acid transport processes in the domestic fowl (Gallus domesticus).

摘要: Intestinal absorption of amino acids in the chicken occurs by way processes which are concentrative, Na+-dependent and dependent upon metabolic energy form ATP. transport is carrier-mediated, subject to exchange (trans-membrane effects) inhibitable sugars, reagents inactivate sulfhydryl groups, potassium ion, deoxpyridoxine, an anti-vitamin B6 agent. It stimulated phlorizin, a potent inhibitor sugar transport, Na+-leached tissue modifiers cyclic AMP levels, e.g. theophylline, histamine, carbachol secretin. Separate sites with broad, overlapping specificities function intestinal various classes common acids. A simple model for these includes one leucine other neutral acids, proline, beta-alanine related imino basic acidic Absorption appears be widespread occurrence digestive tract domestic fowl; has been reported present crop, gizzard, proventriculus, small intestine colon. By end first week life post-hatch, caecum loses its ability transport. Similarly, yolk sac second day post-hatch. was noted before hatch found maximal immediately requirement Ca2+ lost after The cationic appear reabsorbed mechanism kidney. Transport rates measured or erythrocyte were cluster about discrete values when many individual chickens surveyed; such patterns may expression gene differences between individuals. Two lines have developed, high low uptake, through selective breeding based on birds absorb erythrocytes. High absorbing more effective lysine glycine, effectively Na+, had greater K+-ATPase activity, their erythrocytes contained 20% less Na+ than line underlying genetic difference reside at level (or) regulatory determining carrier copies. Amino acid highest pre-hatch chicks diminish during post-hatch development.(ABSTRACT TRUNCATED AT 400 WORDS)