Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy
作者： Charlotte Fristedt Duvefelt
DOI:
关键词:
摘要: This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM not fully understood and there large intra-tumour inter ...
参考文章(152)
J Hardin, S MacLeod, I Grigorieva, R Chang, B Barlogie, H Xiao, J Epstein, Interleukin-6 Prevents Dexamethasone-Induced Myeloma Cell Death Blood. ,vol. 84, pp. 3063- 3070 ,(1994) , 10.1182/BLOOD.V84.9.3063.3063
K. Nilsson, Established Cell Lines as Tools in the Study of Human Lymphoma and Myeloma Cell Characteristics Haematology and blood transfusion. ,vol. 20, pp. 253- 264 ,(1977) , 10.1007/978-3-642-66639-1_31
Vucic D, de Almagro Mc, THE INHIBITOR OF APOPTOSIS (IAP) PROTEINS ARE CRITICAL REGULATORS OF SIGNALING PATHWAYS AND TARGETS FOR ANTI-CANCER THERAPY Experimental Oncology. ,vol. 34, pp. 200- ,(2012)
Garrison Fh, The history of cancer Bulletin of the New York Academy of Medicine. ,vol. 2, pp. 179- 185 ,(1926)
Miguel Lemaire, Sarah Deleu, Elke De Bruyne, Els Van Valckenborgh, Eline Menu, Karin Vanderkerken, The microenvironment and molecular biology of the multiple myeloma tumor. Advances in Cancer Research. ,vol. 110, pp. 19- 42 ,(2011) , 10.1016/B978-0-12-386469-7.00002-5
Guy S. Salvesen, Colin S. Duckett, IAP proteins: blocking the road to death's door Nature Reviews Molecular Cell Biology. ,vol. 3, pp. 401- 410 ,(2002) , 10.1038/NRM830
Thomas E. Witzig, Diane F. Jelinek, Bonnie K. Arendt, A role for insulin-like growth factor in the regulation of IL-6-responsive human myeloma cell line growth. Journal of Immunology. ,vol. 159, pp. 487- 496 ,(1997)
Hua Zou, Yuchen Li, Xuesong Liu, Xiaodong Wang, An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9 Journal of Biological Chemistry. ,vol. 274, pp. 11549- 11556 ,(1999) , 10.1074/JBC.274.17.11549
Shmuel Yaccoby, Bart Barlogie, Joshua Epstein, Primary Myeloma Cells Growing in SCID-hu Mice: A Model for Studying the Biology and Treatment of Myeloma and Its Manifestations Blood. ,vol. 92, pp. 2908- 2913 ,(1998) , 10.1182/BLOOD.V92.8.2908
Alan Lichtenstein, Agnes Gardner, Yiping Tu, The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses. Cancer Research. ,vol. 60, pp. 6763- 6770 ,(2000)