作者: Dilip R. Wagle , Anthony Cerami , Peter C. Ulrich
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摘要: The present invention relates to compositions and method for inhibiting nonenzymatic cross-linking (protein aging) which contain diaminopyridines derivates thereof. Accordingly, a composition is disclosed comprises an agent capable of the formation advanced glycosylation endproducts target proteins by reacting with carbonyl moiety early product such formed their initial glycosylation. contacting protein composition. Both industrial therapeutic applications are envisioned, as food spoilage animal aging can be treated.