Differences in Prevalence of Muscle Weakness (Sarcopenia) in Haemodialysis Patients Determined by Hand Grip Strength Due to Variation in Guideline Definitions of Sarcopenia

摘要: BACKGROUND Muscle weakness is associated with increased mortality, and hemodialysis (HD) patients are at an risk for muscle loss. There no agreed definition weakness, so we determined whether using different cut-off criteria recommended by guideline groups altered the prevalence in HD patients. METHODS We measured hand grip strength (HGS) outpatients, comparing HGS clinical cut-offs (European Working Group on Sarcopenia Older People [EWGSOP] North American Foundation National Institutes of Health Project [FNIH]) used to define wasting (sarcopenia) age-matched gender-matched normative data. RESULTS studied 459 patients, 61.4% male, 47.3% diabetic. The was significantly when measuring HGS; 84.5% EWGSOP 73.2% FNIH criteria, 75.2% data 56.6% U.K. (P < .01). On logistic regression, age (odds ratio [OR] 1.05, P .001), weight (OR 0.96, serum albumin 0.89, = .007), being nondiabetic 0.31, .001). Of comorbidity, 66.7% were weak compared 93.8% highest comorbidity scores CONCLUSION currently universal sarcopenia, but advocate as part their definition. varies according used. In addition, patient characteristics terms determine weakness.