作者: Andreas Mayer
DOI: 10.1146/ANNUREV.CELLBIO.18.032202.114809
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摘要: ▪ Abstract Membrane fusion is a fundamental biochemical reaction and the final step in all vesicular trafficking events. It crucial for transfer of proteins lipids between different compartments exo- endocytic traffic signaling molecules receptors. leads to reconstruction organelles such as Golgi or nuclear envelope, which decay into fragments during mitosis. Hence, controlled membrane reactions are indispensible compartmental organization eukaryotic cells; their communication with environment via hormones, neurotransmitters, growth factors, receptors; integration cells multicellular organisms. Intracellular pathogenic bacteria, Mycobacteria Salmonellae, have developed means control host cells. They persist phagosomes whose lysosomes they actively suppress—a ensure survival inside The past decade has witnessed rapid progress el...