Cardiac myosin heavy chains lacking the light chain binding domain cause hypertrophic cardiomyopathy in mice.
作者： Robert E. Welikson , Scott H. Buck , Jitandrakumar R. Patel , Richard L. Moss , Karen L. Vikstrom
DOI: 10.1152/AJPHEART.1999.276.6.H2148
关键词:
摘要: Myosin is a chemomechanical motor that converts chemical energy into the mechanical work of muscle contraction. More than 40 missense mutations in cardiac myosin heavy chain (MHC) gene and seve...
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