Genome-wide array data and next generation sequencing unravel the etiology of urogenital malformations.
作者： Heiko Reutter , Michael Ludwig
DOI: 10.3233/PGE-12033
关键词:
摘要: Development of the genitourinary tract requires spatiotemporal expression a myriad genes involved in various cascades and signaling events. To date, researchers have put great efforts into defining etiology these malformations. However, many aspects remain unsolved. This paper reviews most recent progress identifying causally related novel loci assumed to harbor formation urogenital These investigations been considerately accelerated by implementation molecular karyotyping using array techniques next generation sequencing strategies.
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