Exercise Hemodynamics in Patients with and without Diastolic Dysfunction and Preserved Ejection Fraction after Myocardial Infarction
作者： Mads J. Andersen , Mads Ersbøll , John Bro-Jeppesen , Finn Gustafsson , Christian Hassager
DOI: 10.1161/CIRCHEARTFAILURE.112.967919
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摘要: Background—Left ventricular diastolic dysfunction (DD) is common after myocardial infarction (MI) despite preservation of left ejection fraction, yet it remains unclear how or whether DD affects cardiac hemodynamics with stress. Methods and Results—Invasive hemodynamic exercise testing was performed in 46 patients a recent MI fraction >45% 10 healthy volunteers. were enrolled prospectively divided into those (MI+DD; atrial volume index >34 mL/m2 E/e′ ratio>8; n=35) without (MI–DD; 15 (14±4 mm Hg), whereas none the MI−DD (10±2 Hg) controls (9±2 displayed pulmonary capillary wedge pressure elevation (P=0.03). During exercise, an abnormal ri...
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