Role of thymus-derived lymphocytes in the secondary humoral immune response in mice.

摘要: THERE is now good evidence that the theta (θ) isoantigen of mice1 carried only by those peripheral lymphocytes which are thymus-derived2–4, so anti-θ antiserum should be useful in elucidating role these cells immunity. In experiments reported here, has been used vitro an adoptive transfer system5 to study function thymus-derived secondary humoral immune response hapten–protein conjugates, particularly terms cellular cooperation and carrier effects.