作者: Sheila Riazi , Natalia Kraeva , Philip M. Hopkins
DOI: 10.1007/S12630-018-1108-0
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摘要: This continuing professional development module aims to prepare anesthesiologists for the timely recognition and management of a malignant hyperthermia (MH) reaction, which is crucial averting its life-threatening complications ultimately patient’s survival. Malignant genetic disorder skeletal muscle cells affecting myoplasmic calcium homeostasis. It can present with nonspecific signs hypermetabolic be fatal if treatment, including administration dantrolene sodium, not implemented promptly. Rapid evaluation rejection alternative diagnoses lead prompt diagnosis treatment therefore will significantly reduce complications, renal failure, cardiac dysfunction, disseminated intravascular coagulation, death. After patients should observed minimum 24 hr because possibility recrudescence. As it condition, survivors their family members referred specialized MH centre further testing counselling. The risk dying from has increased over past few years. A knowledgeable anesthesiologist who diligent attentive recognize an impending reaction treat promptly avoid this deadly condition.