The Atherosclerosis Burden Score (ABS): a Convenient Ultrasound-Based Score of Peripheral Atherosclerosis for Coronary Artery Disease Prediction

摘要: Ultrasonographic detection of subclinical atherosclerosis improves cardiovascular risk stratification, but uncertainty persists about the most discriminative method to apply. In this study, we found that “atherosclerosis burden score (ABS)”, a novel straightforward ultrasonographic sums number carotid and femoral arterial bifurcations with plaques, significantly outperformed common intima-media thickness, mean/maximal carotid/femoral plaque scores for coronary artery disease (CAD) (receiver operating characteristic (ROC) curve area under (AUC) = 0.79; P = 0.027 <0.001 other five US endpoints) in 203 patients undergoing angiography. ABS was also more correlated CAD extension (R = 0.55; P < 0.001). Furthermore, second group 1128 without disease, weakly European Society Cardiology chart categories (R 2 = 0.21), indicating provided information beyond usual factor-based stratification. Pending prospective studies on hard endpoints, appears as promising tool primary prevention.