Generation of Synthetic Elastin-Mimetic Small Diameter Fibers and Fiber Networks

摘要: Elastin-mimetic peptide polymers have been synthesized, and the morphological properties of fabricated small diameter fibers nonwoven fabrics characterized. An 81 kDa recombinant protein based upon repeating elastomeric sequence elastin (Val-Pro-Gly-Val-Gly)4(Val-Pro-Gly-Lys-Gly) was obtained through bacterial expression an oligomerized gene coding for tandem repeats monomer. The processed into by electrospinning technique morphology defined SEM TEM. choice processing parameters influenced both fiber with diameters varying between 200 3000 nm three patterns noted:  beaded fibers, thin filaments, broad ribbonlike structures. Detailed image analysis textile produced from elastin-mimetic revealed that distribution single orientation isotropic associated unimodal diameter. In a dry state, ultimate ...