Rezeptor‐unabhängige Aktivierung von G‐Proteinen

T. Higashijima, J. Burnier, E.M. Ross, Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity. Journal of Biological Chemistry. ,vol. 265, pp. 14176- 14186 ,(1990) , 10.1016/S0021-9258(18)77284-0

Montserrat Camps, Amanda Carozzi, Petra Schnabel, Alexander Scheer, Peter J. Parker, Peter Gierschik, Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits Nature. ,vol. 360, pp. 684- 686 ,(1992) , 10.1038/360684A0

T Higashijima, S Uzu, T Nakajima, E M Ross, Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). Journal of Biological Chemistry. ,vol. 263, pp. 6491- 6494 ,(1988) , 10.1016/S0021-9258(18)68669-7

T Nakamura, M Ui, Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system. Journal of Biological Chemistry. ,vol. 260, pp. 3584- 3593 ,(1985) , 10.1016/S0021-9258(19)83662-1

P Gierschik, D Sidiropoulos, K H Jakobs, Two distinct Gi-proteins mediate formyl peptide receptor signal transduction in human leukemia (HL-60) cells. Journal of Biological Chemistry. ,vol. 264, pp. 21470- 21473 ,(1989) , 10.1016/S0021-9258(20)88206-4

J F Klinker, A Höer, I Schwaner, S Offermanns, K Wenzel-Seifert, R Seifert, Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Biochemical Journal. ,vol. 296, pp. 245- 251 ,(1993) , 10.1042/BJ2960245

M Naim, R Seifert, B Nürnberg, L Grünbaum, G Schultz, Some taste substances are direct activators of G-proteins Biochemical Journal. ,vol. 297, pp. 451- 454 ,(1994) , 10.1042/BJ2970451

S. Böhm, M. Böhm, E. Erdmann, U. Schmidt, P. Gierschik, R. H. G. Schwinger, Sensitization of adenylate cyclase by halothane in human myocardium and S49 lymphoma wild-type and cyc- cells: evidence for inactivation of the inhibitory G protein Gi alpha. Molecular Pharmacology. ,vol. 45, pp. 380- 389 ,(1994)

A. Hagelüken, I. Schwaner, Roland Seifert, L. Grünbaum, D. Höer, Günter Schultz, W. Schunack, S. Offermanns, V. Zingel, A. Höer, The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes. Molecular Pharmacology. ,vol. 45, pp. 578- 586 ,(1994)

Urara Tomita, Atsushi Inanobe, Ichiro Kobayashi, Katsunobu Takahashi, Michio Ui, Toshiaki Katada, Direct interactions of mastoparan and compound 48/80 with GTP-binding proteins. Journal of Biochemistry. ,vol. 109, pp. 184- 189 ,(1991) , 10.1093/OXFORDJOURNALS.JBCHEM.A123342