Potential Therapeutic Effects of Statins in Alzheimer’s Disease

Harry LeVine, III, Richard J. Kryscio, Yushun Lin, Edward Barrett, Elizabeth Head, M. Paul Murphy, Jacqueline Morales, Tina L. Beckett, Giuseppe Astarita, Daniele Piomelli, Adam Weidner, Christa M. Studzinski, Amy L.S. Dowling, Xiaohong Wang, Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs. Journal of Alzheimer's Disease. ,vol. 22, pp. 135- 150 ,(2010) , 10.3233/JAD-2010-100639

Thomas Wallerath, Daniela Poleo, Huige Li, Ulrich Förstermann, Red wine increases the expression of human endothelial nitric oxide synthase: a mechanism that may contribute to its beneficial cardiovascular effects. Journal of the American College of Cardiology. ,vol. 41, pp. 471- 478 ,(2003) , 10.1016/S0735-1097(02)02826-7

Robert G. Riekse, Ge Li, Eric C. Petrie, James B. Leverenz, Darcy Vavrek, Simona Vuletic, John J. Albers, Thomas J. Montine, Virginia M.-Y. Lee, Michael Lee, Peter Seubert, Douglas Galasko, Gerard D. Schellenberg, William R. Hazzard, Elaine R. Peskind, Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid Journal of Alzheimer's Disease. ,vol. 10, pp. 399- 406 ,(2006) , 10.3233/JAD-2006-10408

Rukhsana Sultana, D. Allan Butterfield, Role of Oxidative Stress in the Progression of Alzheimer's Disease Journal of Alzheimer's Disease. ,vol. 19, pp. 341- 353 ,(2010) , 10.3233/JAD-2010-1222

Ge Li, Jane B. Shofer, Isaac C. Rhew, Walter A. Kukull, Elaine R. Peskind, Wayne McCormick, James D. Bowen, Gerard D. Schellenberg, Paul K. Crane, John C.S. Breitner, Eric B. Larson, Age-varying association between statin use and incident Alzheimer's disease Journal of the American Geriatrics Society. ,vol. 58, pp. 1311- 1317 ,(2010) , 10.1111/J.1532-5415.2010.02906.X

Bernadette McGuinness, David Craig, Roger Bullock, Peter Passmore, Statins for the prevention of dementia Cochrane Database of Systematic Reviews. ,(2016) , 10.1002/14651858.CD003160.PUB3

Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima, Ann Bialik, David Fulton, David J. Lefer, William C. Sessa, Kenneth Walsh, The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nature Medicine. ,vol. 6, pp. 1004- 1010 ,(2000) , 10.1038/79510

Sarah D. de Ferranti, Drug Therapy for Hypercholesterolemia and Dyslipidemia Springer, London. pp. 318- 333 ,(2008) , 10.1007/978-1-84628-953-8_13

Juliín Benito-León, Elan D. Louis, Saturio Vega, Félix Bermejo-Pareja, Statins and Cognitive Functioning in the Elderly: A Population-Based Study Journal of Alzheimer's Disease. ,vol. 21, pp. 95- 102 ,(2010) , 10.3233/JAD-2010-100180

SLCO1B1 variants and statin-induced myopathy--a genomewide study The New England Journal of Medicine. ,vol. 359, pp. 789- 799 ,(2008) , 10.1056/NEJMOA0801936