Urbanization and baseline prevalence of genital infections including Candida , Trichomonas , and human papillomavirus and of a disturbed vaginal ecology as established in the Dutch Cervical Screening Program

作者: Mathilde E. Boon , Hedda H. van Ravenswaay Claasen , Lambrecht P. Kok

DOI: 10.1067/MOB.2002.123605

关键词:

摘要: Abstract Objective: An overgrowth of coccoid bacilli in the absence lactobacilli (bacterial vaginosis) is considered a sign “disturbed” vaginal ecologic system. The aim this study was to establish baseline prevalence genital infections and disturbed system their relationship urbanization. Study Design: More than 190,000 cervical smears were screened by 1 cytology laboratory context Dutch national screening programs. women who symptom free had been registered statutory files municipal units invitation. Urbanization (place residence) derived from postal code. To investigate trend relation urbanization, Schaafsma's method used. Results: Bacterial vaginosis highest score per 1000 (36.1), followed Candida (12.6). Higher human papillomavirus, bacterial vaginosis, Trichomonas related urbanization as was, whereas not. Conclusion: Human papillomavirus are more frequently found live large cities, which Netherlands also harbor high-risk population for premalignant cytologic evidence. Our findings concerning pattern support hypothesis importance carcinogenesis. (Am J Obstet Gynecol 2002;187:365-9.)

参考文章(22)
MATHILDE E. BOON, ELISABETH M. MARRES, MARLEEN M. HOOGEVEEN, ANNELIZE F. GOEDBLOED, JAMES MILIOS, Visualization of vaginal flora in cervical smears using a modified microwave silver-staining method. Histochemical Journal. ,vol. 30, pp. 75- 80 ,(1998) , 10.1023/A:1003274815072
Y. T. Van Der Schouw, H. Doornewaard, A. B. Bos, J. G. Van Den Tweel, J. D. F. Habbema, Y. Van Der Graaf, The diagnostic value of computer-assisted primary cervical smear screening: a longitudinal cohort study. Modern Pathology. ,vol. 12, pp. 995- 1000 ,(1999)
Albert J. H. Suurmeijer, Mathilde E. Boon, The Pap Smear ,(1996)
MARTHA L. SLATTERY, JAMES C. OVERALL, THOMAS M. ABBOTT, THOMAS K. FRENCH, LINDA M. ROBINSON, JOHN GARDNER, SEXUAL ACTIVITY, CONTRACEPTION, GENITAL INFECTIONS, AND CERVICAL CANCER: SUPPORT FOR A SEXUALLY TRANSMITTED DISEASE HYPOTHESIS American Journal of Epidemiology. ,vol. 130, pp. 248- 258 ,(1989) , 10.1093/OXFORDJOURNALS.AJE.A115331
Mathilde E. Boon, Harriet Schwinghammer, Gerrita van der Veen, Analysis of Lifestyle Data and Cytologic Findings in a Pilot Cervical Screening Project in Rural Vietnam Acta Cytologica. ,vol. 43, pp. 786- 793 ,(1999) , 10.1159/000331313
GIUSEPPE GIACOMINI, ALESSANDRA CALCINAI, DANIELA MORETTI, RENZA CRISTOFANI, Accuracy of cervical/vaginal cytology in the diagnosis of bacterial vaginosis. Sexually Transmitted Diseases. ,vol. 25, pp. 24- 27 ,(1998) , 10.1097/00007435-199801000-00006
Taha E. Taha, Donald R. Hoover, Gina A. Dallabetta, Newton I. Kumwenda, Laban A. R. Mtimavalye, Li-Ping Yang, George N. Liomba, Robin L. Broadhead, John D. Chiphangwi, Paolo G. Miotti, Bacterial vaginosis and disturbances of vaginal flora: association with increased acquisition of HIV. AIDS. ,vol. 12, pp. 1699- 1706 ,(1998) , 10.1097/00002030-199813000-00019
Mathilde E. Boon, Gerrita van der Veen, Yvonne Barlow, Marcia Silveira Graudenz, Lambrecht P. Kok, Presence of proliferating (MiB-1-positive) cells in cervical smears of women infected with HIV is associated with clinical outcome: a study of Brazilian women. Diagnostic Cytopathology. ,vol. 24, pp. 373- 377 ,(2001) , 10.1002/DC.1083
Poul Thorsen, Inge Panum Jensen, Bernard Jeune, Niels Ebbesen, Magnus Arpi, Annie Bremmelgaard, Birger R. Møller, Few microorganisms associated with bacterial vaginosis may constitute the pathologic core: a population-based microbiologic study among 3596 pregnant women. American Journal of Obstetrics and Gynecology. ,vol. 178, pp. 580- 587 ,(1998) , 10.1016/S0002-9378(98)70442-9