Antibiotic susceptibilities of streptococci from the mouth and blood of patients treated with penicillin or lincomycin and clindamycin.

摘要: Summary Patients undergoing dental extractions were non-randomly allocated to three groups, one of which received no antibiotic, benzylpenicillin followed by oral penicillin for 5 days, and the third intramuscular lincomycin clindamycin. Dental extraction was performed at beginning course chemotherapy. Streptococci isolated from extracted teeth, blood cultures collected before immediately after extraction, sutures removed gums 5-7 days operation. The species these organisms determined, their susceptibilities penicillin, clindamycin, cephaloridine, erythromycin tetracycline assessed. The majority streptococci teeth belonged Streptococcus sanguis, S. mitior, mutans milleri. Occasional isolates each antibiotic could take effect resistant penicillin. Three species, but not mutans, commonest be extraction. Penicillin completely suppressed bacteriaemia under conditions our investigation, reduced incidence about 60 per cent. The also milleri; faecalis isolated, only in patients who had antibiotics. Among non-faecalis organisms, resistance significantly more frequent among given than this clindamycin