Endothelial and Hematopoietic Cells in the Intraembryonic Compartment
作者： Fumio Arai , Toshio Suda
DOI: 10.1007/978-0-387-33535-3_8
关键词:
摘要: The development of endothelial cells and hematopoietic is closely related at embryonic stages, both share a common precursor, the hemangioblast. Differentiation into lineages begins with proliferation single layer mesodermal in yolk sac resulting formation cell clusters, blood islands. Cells periphery these aggregations differentiate angioblasts. Blood vessels are formed by two different steps, vasculogenesis angiogenesis. interior islands become primitive (HCs). Definitive hematopoiesis develops from P-Sp region as early E8.5. By El0.5, stem (HSCs) originate aorta-gonad-mesonephros (AGM) region. HSCs this colonize fetal liver then move to spleen bone marrow. In embryo, HCs form clusters associated often adhering on ventral surface (floor) aorta. that also appear be derived P-Sp. addition, have been identified vitelline umbilical arteries, indicating intraembryonic major arterial embryo.
springer.com
sci-hub.st 参考文章(87)
Harvey R, Green Ar, Begley Cg, Visvader J, Lints T, SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain. Oncogene. ,vol. 7, pp. 653- 660 ,(1992)
Andrew G. Elefanty, C. Glenn Begley, Lynne Hartley, Bette Papaevangeliou, Lorraine Robb, SCL expression in the mouse embryo detected with a targeted lacZ reporter gene demonstrates its localization to hematopoietic, vascular, and neural tissues. Blood. ,vol. 94, pp. 3754- 3763 ,(1999) , 10.1182/BLOOD.V94.11.3754
PE Young, S Baumhueter, LA Lasky, The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development. Blood. ,vol. 85, pp. 96- 105 ,(1995) , 10.1182/BLOOD.V85.1.96.BLOODJOURNAL85196
AR Kallianpur, JE Jordan, SJ Brandt, The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis Blood. ,vol. 83, pp. 1200- 1208 ,(1994) , 10.1182/BLOOD.V83.5.1200.1200
Begley Cg, Visvader J, Adams Jm, Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system. Oncogene. ,vol. 6, pp. 187- ,(1991)
Heather B. Wood, Gillian May, Lyn Healy, Tariq Enver, Gillian M. Morriss-Kay, CD34 expression patterns during early mouse development are related to modes of blood vessel formation and reveal additional sites of hematopoiesis. Blood. ,vol. 90, pp. 2300- 2311 ,(1997) , 10.1182/BLOOD.V90.6.2300
SH Orkin, GATA-binding transcription factors in hematopoietic cells Blood. ,vol. 80, pp. 575- 581 ,(1992) , 10.1182/BLOOD.V80.3.575.BLOODJOURNAL803575
Peter Carmeliet, Mechanisms of angiogenesis and arteriogenesis. Nature Medicine. ,vol. 6, pp. 389- 395 ,(2000) , 10.1038/74651
M Tavian, L Coulombel, D Luton, HS Clemente, F Dieterlen-Lievre, B Peault, Aorta-associated CD34+ hematopoietic cells in the early human embryo Blood. ,vol. 87, pp. 67- 72 ,(1996) , 10.1182/BLOOD.V87.1.67.67
Douglas Hanahan, Signaling Vascular Morphogenesis and Maintenance Science. ,vol. 277, pp. 48- 50 ,(1997) , 10.1126/SCIENCE.277.5322.48