Smoking mentholated cigarettes impairs coronary microvascular function as severely as does smoking regular cigarettes.

摘要: Objective — Smoking mentholated cigarettes inhibits the metabolism of nicotine and increases systemic exposure to cigarette smoke toxins. However, possible effects smoking on coronary microvascular functions are unknown.We sought investigate whether impairs flow reserve (CFR) more so than regular cigarettes.Methods Twenty otherwise healthy smokers (6 women, 14 men; mean age, 25.6 ± 6.4 years) 22 non-smoking control subjects were included in study.To compare acute (0.9 mg nicotine, 11 tar, 12 carbon monoxide) CFR, all underwent an echocardiographic examination that CFR measurements at baseline. 30 minutes after had smoked 2 cigarettes, was again measured group.Results In response t...