Calcium: The Answer to Life, the Universe, and Everything

摘要: Calcium plays a critical role in numerous physiological processes, both inside and out of the nervous system, thus is widely studied by experimental theoretical neuroscientists. While calcium system has been experimentalists for many decades, last 20 years seen considerable growth use computational modeling as tool to unravel complex cellular mechanisms requiring calcium. For example, enhanced our understanding processes such release neurotransmitter excitation–contraction coupling myocytes. Long-term synaptic plasticity control neuronal activity patterns are two additional functions that particular interest This chapter presents brief history studies investigate either relationship between long-term plasticity, or firing patterns. The focus on subset models made advancements form model addressing novel scientific question.