作者: Tina YT Chen , Stephen Morrell , Wendy Thomson , Deborah F Baker , Richard Walton
DOI: 10.1111/AJR.12172
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摘要: Objective This study aims to compare survival from breast, colon, lung, ovarian and rectal cancer by geographical remoteness in New South Wales (NSW). Design Retrospective population-wide registry study. Setting NSW, Australia. Participants A total of 107 060 NSW residents, who were diagnosed with any the five cancers between 01 January 2000 31 December 2008. Main outcome measures Kaplan–Meier curves proportional hazards regression used residence at diagnosis, controlling for gender, age extent disease diagnosis. Remoteness was classified using standard definitions: major city, inner regional (InnReg), outer (OutReg) remote (including very remote). Results Significant differences (likelihood death) identified all cancers: breast (adjusted hazard ratio(HR) = 1.22 (95% confidence interval (CI), 1.001–1.48) regionalised HR = 1.30 (1.02–1.64) metastatic OutReg areas); colon (HR = 1.14 (1.01–1.29) areas disease); lung (HR range = 1.08–1.35 (1.01–1.48) most non-metropolitan stages excepting regionalised); (HR = 1.32 (1.06–1.65) disease, HR = 1.40 (1.04–1.90) InnReg 1.68 (1.02–2.77) unknown stage disease) (HR = 1.37 (1.05–1.78) localised HR = 1.14 (1.002–1.30) disease). Where significant found, cities tended show best survival, whereas worst. Although no definitive interpretation could be made regarding due small patient numbers, their appeared relatively favourable. Conclusions Reasons that contribute observed disparate results types need further explored order facilitate targeted solutions reducing inequality regions.