Use of Peptides for the Management of Alzheimer’s Disease: Diagnosis and Inhibition
作者： Mohammad H. Baig , Khurshid Ahmad , Gulam Rabbani , Inho Choi
关键词:
摘要: Alzheimer's disease (AD) is a form of dementia and the most common progressive neurodegenerative (ND). The targeting amyloid-beta (Aβ) aggregation one widely used strategies to manage AD, efforts are being made globally develop peptide-based compounds for early diagnosis treatment AD. Here, we briefly discuss use AD inhibitors various Aβ checkpoints. In addition, recent applications against targets including amyloid beta, β-site precursor protein cleaving enzyme 1 (BACE1), Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), tyrosine phosphatase (TP) potassium channel KV1.3.
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