Minimal Clinically Important Differences for PROMIS Physical Function, Upper Extremity, and Pain Interference in Carpal Tunnel Release Using Region- and Condition-Specific PROM Tools

摘要: Purpose Uncertainty exists about what change in Patient-Reported Outcomes Measurement Information System (PROMIS) scores represents a clinically relevant improvement (minimal important difference [MCID]) hand surgery care. Using region-specific patient-reported outcome measure (PROM) (Michigan Hand Question [MHQ]) and condition-specific PROM (Boston Carpal Tunnel Questionnaire [BCTQ]), MCID values were determined for PROMIS Physical Function (PF), Upper Extremity (UE), Pain Interference (PI) computerized adaptive testing among patients undergoing carpal tunnel release (CTR). Methods Patients CTR with single surgeon from November 2014 to April 2017 asked complete the BCTQ, MHQ, PF, UE, PI at each visit. who had completed questionnaires both preoperative either 6-week or 3-month postoperative visit included. The calculated using previously estimates literature region- (ie, MHQ) BCTQ) anchors. domain also distribution-based method. Results A total of 70 fit our inclusion criteria. MHQ Pain, MCIDs 6.3, 1.8, –8.9, respectively. average 2 BCTQ domains, 8.0, 2.8, –9.7, method, 4.2, 2.7, and –4.1, Conclusions PROMs, we able provide CTR. Clinical relevance Estimating validated PROMs provides surgeons way evaluate outcomes not described literature. Surgeons should understand that these are only future work is needed verify whether they reflect clinical improvement.