Hydantoin derivatives for treating complications of diabetes

作者: Kiichi Sawai , Kyoichi Asano , Kuniharu Mizuno , Yasuaki Kondo , Naofumi Terada

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摘要: Hydantoin derivatives and salts thereof, intermediates therefor, process for the preparation medicines containing derivative, wherein said have formula one of V W is hydrogen other a halogenomethyl group, 1 H-tetrazol-5-yl radical, -COOR in which R atom, an alkyl -(CH2CH2O)nCH3 group (n integer to 113) or substituted phenyl, R1 R2 are same different independently, each phenyl has meaning as referred to) may form heterocyclic ring together with nitogen oxygen -CH2OR3 R3 Ra independently atom X sulfur Y Z halogen alkoxy alkylmercapto nitro radical -NHR5 R5 acyl group. The thereof useful treatment complications diabetes.

参考文章(4)
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Kiyoshi Watanabe, Yoshio Shimada, Yasuhiro Katayama, Yasuyoshi Ueda, Satomi Takahashi, Yukio Yamada, Process for preparing optically active hydantoins ,(1985)
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