作者: Ruey J. Yu , Eugene J. Van Scott
DOI:
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摘要: Topical compositions and methods including non-amphoteric derivatives of glutathione, for example, N-acyl-glutathiones, N-acyl-glutathione amides, esters are disclosed use in the treatment prevention cosmetic conditions dermatological disorders, disclosed. The glutathione may have structure (I): R' -COCHNH (R2) H2CH2CONHCH(CH2SR3) CONHCH2 CO-R' wherein is independently selected from -OH, -NH2, -NHNH2, an alkoxyl group, aralkoxyl aryloxyl group R2 R3 each a hydrogen atom or acyl but if at least one then group.