Effect of symptoms on executive function in bipolar illness

摘要: Background. The relationship between cognitive function and symptomatology in bipolar disorder is unclear. This study assessed executive during the manic, depressed remitted stages of I disorder. Method. Tasks assessing phonological semantic verbal fluency, Hayling Sentence Completion Test, Stroop Neuropsychological Screening Test Cognitive Estimates were administered to manic ( n =15), =15) patients, healthy controls =30). Multiple regression analyses covariance used identify potential determinants dysfunction three groups. Results. Executive deficits particularly associated with state. In general, patients performed less accurately than groups, their performance deficit was related severity positive thought groups showed a widespread pattern impairment. Deficits response initiation, strategic thinking inhibitory control evident all Conclusions. are most mania, formal However, may be more underlying particular symptom profile.