Postmortem redistribution of digoxin in rats.

作者: Gideon Koren , Stuart M. MacLeod

DOI: 10.1520/JFS10968J

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摘要: Adult male Wistar rats were treated with either 0.1 or 3 mg/kg body weight · day of digoxin for five days, then killed and stored at 4°C 12 h in an attempt to mimic the normal preautopsy procedures our hospital. In day, antemortem serum concentrations (SDC) 1.1 ± 0.4 ng/mL while 12-h postmortem concentration was markedly increased (16.3 5.9 ng/mL) (P

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