2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same

摘要: Compounds represented by general formula (I), pharmaceutically acceptable acid addition salts thereof, or hydrates of the same; drugs containing these compounds; medicinal compositions compounds together with carriers; and 2-amino-2-(2-(4-(1-hydroxy-5-phenylpentyl)phenyl)ethyl)propane-1,3-diol 2-amino-2-(2-(4-formylphenyl)ethyl)-propane-1,3-diol optionally protected at amino and/or hydroxy group each useful as an intermediate in synthesizing above compounds. In said formula, R?1, R2, R3 R4? represent hydrogen acyl. Because having little toxicity, high safety excellent immunosuppressive effects, are preventives depressants for rejection reactions organ bone marrow transplantations remedies various autoimmune diseases, allergic etc.