作者: Jeffrey L Cummings , Gustavo Alva
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摘要: Objective: In the US, approved therapies for mild to moderate Alzheimer’s disease (AD) currently comprise three cholinesterase inhibitors (ChEIs: donepezil, galantamine, and rivastigmine), while N-methyl-D-aspartate (NMDA) receptor antagonist memantine ChEI donepezil are severe AD. The purpose of this study is review safety tolerability ChEIs memantine, based upon manufacturers’ data found in prescribing information (PI) documents. Design: Current PI documents