The Ultrastructure of Mitochondria

摘要: The study, in thin sections, of the specific morphology mitochondria different plant and animal cells has confirmed view that, spite a wide polymorphism gross structure, organelle is nevertheless built according to same fundamental pattern, which was first described by Palade (1953) Sjostrand (1953). As seen most electron micrographs sectioned fixed cells, appear consist double membrane system two distinct compartments; an outer compartment, varying relative importance, comprises space between membranes mitochondrial envelope intracristal spaces, inner compartment or matrix separated from cytoplasm (plate 14, ). Many aspects recent research on deal with correlations form function, changes occurring during cell differentiation, hormone-induced alteration respiratory adaptation. There no place here mention all this interesting matter I shall restrict my subject few additions corrections have been brought basic already classical scheme mitochondrion. But, restricted study generalized mitochondrion, not confine myself mere description material, but also consider how related techniques increased our understanding fine structure discuss implications relation concept living organelle. Osmotic swelling post-mortem alterations subcellular organelles are important sources misinterpretation ultrastructure. Sample preparation very quick freezing substitution (Malhotra 1966) greatly improves conservation and, using technique immediately after killed, it shown that closely applied one another: confirms vivo , only potential existence.