Novel 2-pyrazoline derivatives as potential antibacterial and antifungal agents

摘要: The 1,3,5-trisubstituted-2-pyrazolines were synthesized by refluxing isoniazid with various substituted diarylchalcones in N,N-dimethylformamide at 120-140°. physical and spectral data such as M.P., R f , elemental analysis, IR, NMR Mass was obtained for the compounds structures confirmed. screening of antimicrobial activity performed against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli Aspergillus niger .